Retino-A is the most commonly used Tretinoin cream in India. Tretinoin is an acid form of Vitamin A usually prescribed for acne vulgaris, acne scar treatment and sun-damaged skin.
Retino-A cream 0.05% is used to treat acne vulgaris by preventing the formation and spread of pimples and blackheads (comedones). Retino-A cream 0.05% is also used to help reduce visible signs of ageing on the face by fading age spots and reducing fine wrinkles, as it promotes skin turnover to replace old damaged skin with new skin.
Retino-A cream 0.05% also has a potential use for treatment of alopecia (hair loss).
Retino-A cream 0.05% contains the active ingredient tretinoin, which is a keratolytic medication that is used to reduce symptoms of acne as well as age spots and fine wrinkles.
Mechanism of action
Retino-A cream 0.05% contains tretinoin which is an active metabolite of Vitamim A and is a keratolytic medication that affects the way skin cells behave, reducing symptoms of acne as well as age spots and fine wrinkles caused by sun damage and aging. Retino-A cream 0.05% prevents formation of new pimples and blackheads (comedones) by blocking the hardening processes of the outer skin layer (keratinisation and cornification) and increasing the shedding of old hardened skin cells, while at the same time promoting growth of new skin cells. The combined effect of these actions is to speed up skin cell turnover, clear up pimples and blackheads and reduce the spread of acne. This also works for aging or damaged skin where age spots and fine wrinkles are replaced by new skin cells giving the effect of lightening and smoothing the skin.
How to apply the cream
Retino-A cream 0.05% should be applied to the affected area of the skin once daily, preferably in the evening before going to bed. Clean the skin with a mild soap or soap-free cleanser, rinse with water then apply a small amount with clean fingers and rub gently into the skin. Do not use large amounts or apply Retino-A 0.05% more often than directed, as your skin will not clear up faster, instead you may increase the chance for side effects like skin irritation. Avoid contact with the eyes, eyelids, inside of the nose and mouth, which are easily irritated areas, or other areas where treatment is not intended. Do not apply to severely inflamed skin or to open lesions.
• A brief sensation of warmth or stinging may occur immediately after applying the medication.
• Skin redness, dryness, itching, scaling, mild burning, or worsening of acne may occur during the first 2-4 weeks of using the medication. These effects usually decrease with continued use.
• If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Your doctor may want you to decrease how often you use tretinoin, change the strength or type, or have you stop using it.
Many people using this medication do not have serious side effects.