Sildigra 50 is an oral medication used to treat erectile dysfunction in male. This medicine accompanies a best and reliable fixing called sildenafil citrate 50mg. The fundamental propose of this medicine is to build the blood stream level into the male organ to make the organ harder and hold the arousing erection for quite a while. In today’s world, a considerable men population is experiencing erectile related issues and they feel the disgrace of sharing their issues to specialist or with others. These sorts of issues can likewise influence your love connection. This medicine is made with a clean and new fixing to fix your illness adequately.
Dosage of Sildigra 50mg:
- The dose and length of the medication are exhorted by the specialist. One can devour the medication with a glass of water before arousing activity.
- Make an effort not to skip or miss the measurements.
- Utilization of a lacking measure of medication should be avoided.
- Stay away from high-fat feast, oily food with the utilization of medicine.
- The measurement of the medication requires an hour for agreeable outcomes and goes on for over 4 hours.
Mechanism Of Action:
The physiologic mechanism of erection of the penis involves release of nitric oxide (NO) in the corpus cavernosum during sexual stimulation. NO then activates the enzyme guanylate cyclase, which results in increased levels of cyclic guanosine monophosphate (cGMP), producing smooth muscle relaxation in the corpus cavernosum and allowing inflow of blood.
Sildenafil enhances the effect of NO by inhibiting phosphodiesterase type 5 (PDE5), which is responsible for degradation of cGMP in the corpus cavernosum. When sexual stimulation causes local release of NO, inhibition of PDE5 by sildenafil causes increased levels of cGMP in the
corpus cavernosum, resulting in smooth muscle relaxation and inflow of blood to the corpus cavernosum. Sildenafil at recommended doses has no effect in the absence of sexual stimulation.
How to take the medicine:
The usual recommended dose is 50 mg taken as needed, approximately 30 to 60 minutes before sexual activity. However, the medication may be taken any time from 4 hours to half an hour before sexual activity.
Sildenafil may be taken with or without food, but taking it with a high-fat meal may increase the time before the medication starts working.
Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications.
It is important to take this medication exactly as prescribed by your doctor. Do not take higher doses of this medication than those prescribed by your doctor. Contact your doctor if you take a greater dose of sildenafil than prescribed.
Do not take sildenafil if you:
are allergic to sildenafil or any ingredients of this medication
are taking any type of nitrate medication in any form (oral, sublingual, skin patch, or spray). Nitrate medications include nitroglycerin and related medications that are used for the relief of chest pain or angina. Use of these medications with sildenafil could cause a sudden severe drop in blood pressure that could lead to dizziness, fainting, heart attack, or stroke.
have been advised by your doctor not to engage in sexual activity
Side effects can be mild or severe, temporary or permanent. Side effects of sildenafil include warmth or redness in the face, neck, or chest; stuffy nose; headaches, stomach pain, nausea, diarrhea, and an inability to differentiate between the colors green and blue. Loss of hearing, ringing in the ears and dizziness are other potential side effects.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
During sexual activity, if you become dizzy or nauseated, or have pain, numbness, or tingling in your chest, arms, neck, or jaw, stop and call your doctor right away. You could be having a serious side effect of sildenafil.
Stop using sildenafil and call your doctor at once if you have a serious side effect such as:
sudden vision loss;
ringing in your ears, or sudden hearing loss;
chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling;
Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.
Consumption of alcohol in large amounts may decrease the ability to get an erection and may also temporarily decrease blood pressure, causing dizziness and fainting.
Tell your doctor if you are taking medications to treat high blood pressure. The combination of these medications and sildenafil may add to the blood pressure-lowering effect of these medications. You should also let your doctor know if you have or have had low blood pressure.
Grapefruit juice can increase the amount of sildenafil in your bloodstream. Do not drink grapefruit juice when taking this medication.