Fildena 150, a popular brand of sildenafil citrate is a drug used mainly for the treatment of the erectile dysfunction in men. Erectile dysfunction (ED) commonly known as impotence, a sexual disability in which a man is unable of obtaining or holding an erection during sexual intercourse.
Mechanism Of Action
The physiologic mechanism of erection of the penis involves release of nitric oxide (NO) in the corpus cavernosum during sexual stimulation. NO then activates the enzyme guanylate cyclase, which results in increased levels of cyclic guanosine monophosphate (cGMP), producing smooth muscle relaxation in the corpus cavernosum and allowing inflow of blood.
Sildenafil enhances the effect of NO by inhibiting phosphodiesterase type 5 (PDE5), which is responsible for degradation of cGMP in the corpus cavernosum. When sexual stimulation causes local release of NO, inhibition of PDE5 by sildenafil causes increased levels of cGMP in the
How to take the medicine
Fildena 150 comes in tablet form and is taken orally. Take the preferred dosage with a full glass of water and preferably on an empty stomach. Swallowing the table without food will improve the ability to absorb the medication.
Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications.
It is important to take this medication exactly as prescribed by your doctor. Do not take higher doses of this medication than those prescribed by your doctor. Contact your doctor if you take a greater dose of sildenafil than prescribed.
Do not take sildenafil if you:
- are allergic to sildenafil or any ingredients of this medication
- are taking any type of nitrate medication in any form (oral, sublingual, skin patch, or spray). Nitrate medications include nitroglycerin and related medications that are used for the relief of chest pain or angina. Use of these medications with sildenafil could cause a sudden severe drop in blood pressure that could lead to dizziness, fainting, heart attack, or stroke.
- have been advised by your doctor not to engage in sexual activity
Fildena 150mg tablet are generally well tolerated but it is always possible that you may experience side effects.ocular events,
- Transient altered colour vision (chromatopsia and cyanopsia) is a known dose-related effect believed to be attributable to PDE6 inhibition in the retina
|US Brand Name||Sildenafil Citrate|
|Generic Name||Sildenafil Citrate|