Arzep 10 ml
Arzep Nasal Spray contains the active ingredient azelastine (0.1%w/v), an antihistamine used to treat nasal symptoms of allergic rhinitis, in a CFC-free spray. Arzep Nasal Spray is an antihistamine that prevents allergic reactions and reduces inflammation. It does not prevent the body from releasing histamine but it blocks histamine from binding to receptors in the body.It is used to treat allergic rhinitis, which is an allergic reaction causing irritation and inflammation of the nasal passages. Allergic rhinitis can be seasonal caused by pollen (hay fever) or perennial caused by allergens such a house dust mites, mould or animal fur. Arzep Nasal Spray acts locally on the nasopharyngeal passages to relieve symptoms including increased mucous production, nasal swelling and congestion, runny itchy nose and sneezing.
Mechanism of action
Arzep Nasal Spray contains azelastine, which is a potent, fast-acting, long-acting antihistamine that blocks the action of histamine, a chemical released from mast cells, in response to allergens like pollen during an allergic reaction. Histamine binds to the H1 receptor in small blood vessels in the nasal passages causing them to leak, allowing white blood cells and blood proteins into the tissues, causing inflammation, tissue swelling, over production of mucus and irritation. Azelastine in Arzep Nasal Spray binds to H1 receptors and blocks histamine-mediated actions, as well as acting directly on the mast cells to reduce the amount of histamine released. This dual action of Arzep Nasal Spray reduces nasal symptoms of allergic rhinitis like nasal congestion, runny itchy nose and sneezing.
Arzep Nasal Spray should be administered 1 to 2 times per day in each nostril. Dosage usually depends on the severity of the patients symptoms, contact a doctor for the correct dosage. Prior to the initial application or if the medication has not been used for 3 days, the spray will need to be primed before use. To prime the bottle, simply point the spray away from the face and apply 3 gentle pushes to the bottle. To apply the medication, the patient should blow their nose gently before application. Put the nozzle in 1 nostril, gently press down on the opposite nostril with your finger then pump the spray and inhale at the same time. The patient should avoid sneezing or blowing their nose directly after application of the medication.
Patients using Arzep Nasal Spray may encounter side effects such as:
- Burning feeling inside nose
You should not use Arzep Nasal Spray if you:
- are allergic to azelastine or any ingredients in Arzep Nasal Spray
- are pregnant or are breastfeeding, without discussion with your doctor
- are taking any medications that interact with azelastine in Arzep Nasal Spray, including CNS depressants, cimetidine and also alcohol
You should store your Arzep Nasal Spray below 25°C in a cool dry place but do not refrigerate.